kevin wrote:With "in Hamburg", I feel there isn't much difference in neutrality, but in both sentences the place is important. Anyway, Er besucht in Hamburg seine Familie is likely the answer to "Was tut er in Hamburg?", whereas Er besucht seine Familie in Hamburg is the answer to "Wo besucht er seine Familie?" bzw. "Wo ist die Familie, die er besucht?" I guess that's topicality at work again?
Genau. In the first instance, in Hamburg is known information, so it moves to the front of the middle field, making room for new information at the end.
I feel like we should check in with the OP at this point to find out whether any of this discussion is helping them. (Not that we should put an end to it if it's not--this is all very useful information--but I don't want to lose sight of the raison d'être for this thread.)